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The role of colostral antibodies in prevention of microbial infections.

The role of colostral antibodies in prevention of microbial infections.









No. Divisions/Titles for Abstract Details

1 Abstract Title The role of colostral antibodies in prevention of microbial infections.


2 Abstract Source Current opinion in infectious diseases, 14, 295-300.


3 Abstract Author(s) Lilius, E.-M. & Marnila, P.


4 Article Affiliation Department of Biochemistry and Food Chemistry, University of Turku, Turku, and bAgricultural Research Centre of Finland, Food Research, Jokioinen, Finland.


5 Abstract Mammalian colostrum offers passive protection to the newborn against a variety of microbial pathogens, in the form of specific immunoglobulin A, G and M antibodies. Sharing maternal immunological memory is in many cases vital for the infant, but may have disastrous consequences, such as involuntary transfer of disease and disturbance of the developing immune system. In most published studies, immune milk preparations are reported to be effective in the prevention of various gastroenteric infections, but not in the treatment of an established infection.


6 Summary Colostral antibodies can induce phagocytosis and killing of pathogens by leukocytes, and can prevent the attachment of pathogen to the epithelial lining, a critical step in the establishment of infection. Promising therapeutic effects have been reported in diseases in which infection is maintained through constant reattachment and reinfection (e.g. inside the oral cavity or the gastrointestinal lumen) and in which toxins or inflammatory compounds are involved that can be neutralized by the specifc immunoglobulins in colostral preparations.


7 Article Published Date Jan-2001.


8 Study Type review.


9 Substances colostrum.


10 Diseases microbial infections , gastroenteric infections.


11 Pharmacological Actions anti microbial by antibodies.


12 Link https://goo.gl/mgKUdF








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